Low Molecular Weight Sodium Hyaluronate: This smaller-sized form enhances the healing rate of the affected region in the colon through epithelial restitution, aiding recovery at the muscosal level which is affected by UC.
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TRUD™ is a white enema bottle containing a thick suspension that includes sodium hyaluronate and is used to relieve the symptoms of mild to moderate ulcerative colitis. Ulcerative colitis is a disease of the colon and rectum in which the mucosal lining becomes inflamed.
Symptoms include rectal bleeding, frequent diarrhoea and abdominal pain. TRUD™ is applied via the rectum and forms a protective coat over the lining of the distal colon and rectum.This allows the mucosal tissue to heal naturally which reduces the symptoms of ulcerative colitis.
TRUD™ contains two specific types of Sodium Hyaluronate (Hyaluronic Acid) and a natural muco-adhesive agent for prolonged adherence to the mucosa. Its effectiveness in treating mild to moderate Ulcerative Colitis (UC) is attributed to two key properties related to the size of Sodium Hyaluronate:
Low Molecular Weight Sodium Hyaluronate: This smaller-sized form enhances the healing rate of the affected region in the colon through epithelial restitution, aiding recovery at the muscosal level which is affected by UC.
High Molecular Weight Sodium Hyaluronate: This larger-sized form adheres to inflamed areas, protecting them from bacteria and toxins during healing, reducing further inflammation.
TRUD™ can be bought at your local pharmacy as a CE-marked Class IIa medical device. While no prescription is needed, it’s highly recommended to consult your doctor if you are thinking of using it for the first time. Contact us if you are unable to find it at your local pharmacy.